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W16-022: Evaluating new drug compounds for treating feline coronavirus, a continuation study

This is a continuation study of a previous Winn-funded grant (W15-010). Feline infectious peritonitis (FIP) is a common and generally lethal disease of domestic cats for which there currently is no effective treatment. A laboratory method has been developed to test drug compounds for their effectiveness against FIP. Multiple drug compounds have demonstrated to be effective against SARS and/or MERS, human infections caused by viruses similar to FIP. In light of the dramatic success in antiviral therapeutics targeted against HIV, many researchers in the FIP field consider antiviral therapy to be the brightest hope for success. Production in the laboratory of a key FIP-specific enzyme will form the basis of a more sophisticated screening test in order to identify drug compounds that will effectively treat FIP. (Bria Fund Study)

Grant ID: W16-022

Status: Active

Year Funded: 2016

Amount awarded: $12,175

Investigator: Brian Murphy, DVM, PhD, ACVP; Niels Pedersen, DVM, PhD; University of California, Davis