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W12-039: Administration of pimobendan to cats with chronic kidney disease

Chronic kidney disease (CKD) is one of the most common reasons geriatric cats present to the veterinarian. CKD is considered irreversible and progressive, and effective treatments are limited. A common co-­‐existing condition often appreciated in feline CKD patients is heart disease. Two of the investigators in this study have administered pimobendan to cats with combined kidney and heart disease. The patients had developed congestive heart failure (CHF) secondary to intravenous fluid administration, a typical standard of care for kidney disease. In some of these patients, addition of pimobendan resulted in a greater improvement in kidney values and clinical response. Tolerability and safety of this drug has already been established in cats with heart disease. This will be a pilot study to assess the tolerability of pimobendan in cats with CKD and search for benefits in comparison to the current standard of care. Investigating these observations in a larger study will help establish whether pimobendan could be a novel treatment for cats with CKD.

Grant ID: W12-039

Status: Active

Year Funded: 2012

Amount awarded: $20,000

Investigator: Mary Anna Labato, DVM, DACVIM; Brandi R. Gallagher, DVM; John Rush DVM, MS, DACVECC, DVM; Tufts University College of Veterinary Medicine