Immunotherapy uses the body’s immune system, either directly or indirectly, to fight cancer. It has the potential ability to act on the primary tumor as well as metastasis. Interleukin 12 (IL 12) is a protein that belongs to the family of substances known as cytokines. Various studies have shown that IL 12 is effective in the treatment of some tumors. These investigators will develop a novel system to deliver gene therapy directly to the site of the tumor.