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W04-022: Comparison of the rDNA ITS-1 and ITS-2 regions of different isolates of C. felis with varying pathogenicity

Cytauxzoon felis is a protozoal disease affecting domestic cats primarily seen in the south-central United States. The disease is tick-transmitted and, until recently, reported to be nearly 100% fatal. Once a tick has given the disease to a cat, there is rapid progression and death occurs within a week, with or without treatment. Recently, cases of domestic cats in a certain geographic location in western Arkansas and eastern Oklahoma have survived the disease and appear to have developed immunity. It is thought these cats are infected with a less aggressive strain of Cytauxzoon felis. Currently, there is no way to differentiate the different strains of the organism, and these researchers will develop a test.

Grant ID: W04-022

Status: Active

Year Funded: 2004

Amount awarded: $2,750

Investigator: Theresa E. Rizzi, DVM; Mason Reichard, PhD; James H. Meinkoth, DVM, PhD, DACVP and A. Alan Kocan, MSPH, PhD; Oklahoma State