A high-density DNA array for the domestic cat is in development. This array is thirty-times more powerful than the previous cat DNA array. Through genome-wide association studies (GWAS) which use such DNA arrays, DNA variants (or mutations) influencing traits can be localized. This project will focus on the condition of amyloidosis in Oriental/Siamese cats to narrow down the region(s) of the genome associated with this disease. In addition, worldwide populations of cat breeds, especially Burmese, will be scanned for a DNA variant correlating with Ehrlos-Danlos Syndrome where a genetic test can be developed.
EveryCat Health Foundation has combined funding from the Miller Trust and the Andorra Fund with sponsorship from the Southern California Burmese Cat Club to fund this grant.