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MT20-008: Development of improved cell culture systems for feline coronavirus and FIP vaccine development

FIP is a devastating disease of cats and considerable knowledge about the disease is still a mystery. FIP virus replicates poorly in the laboratory, which limits the ability to understand the mechanisms underlying the disease process. With this study, researchers hypothesize that FIPV type I enters cells, including macrophages, through the ACE2 receptor, as has been determined with SARS-CoV-2 in people. They propose to show that ACE2 and host proteases are key drivers of viral pathogenesis in FIP.

Grant ID: MT20-008

Status: Active

Year Funded: 2020

Amount awarded: $17,500

Investigator: Gary Whittaker, Cornell University; Susan Baker, Loyola University