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MT14-013: Improving the effectiveness of chemotherapy on feline injection site sarcomas

Feline injection site sarcomas (ISS) are aggressive cancers that can occur at the site of injections. They grow quickly and invasively. Radical surgery and/or radiation therapy are often required and still do not necessarily result in cures. The role of chemotherapy in treatment is not well defined and there is little data supporting a positive impact on outcome. This study looks at ways to increase the beneficial effect of chemotherapy by evaluating a variety of therapeutic combinations on cancer cells. The combinations are designed to inhibit the way cancer cells recognize and respond to DNA damage inflicted by the chemotherapeutic.

Grant ID: MT14-013

Status: Active

Year Funded: 2014

Amount awarded: $12,969

Investigator: Kelly Hume; Cornell University