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EC25F-400: Genetic characterization of feline hemoplasma isolates from client-owned cats in Thailand using the RNase P RNA(rnpB) gene

Feline hemoplasmosis is the disease caused by blood-borne pathogens, hemotropic Mycoplasma spp., or hemoplasmas. This group of blood parasites infects and destroys red blood cells. At least three hemoplasma species have been documented: Mycoplasma haemofelis (Mhf), ‘Candidatus Mycoplasma haemominutum’ (CMhm),and ‘Candidatus Mycoplasma turicensis’ (CMt). However, using other genetic markers, for example the 23S rRNA gene, revealed closely related species to CMhm. To confirm these results from the 23S rRNA gene, using the RNase P RNA (rnpB) gene may help to identify actual species of hemoplasmas and demonstrate high diversity of circulating hemoplasma species in cats. Actual species identification of feline hemoplasmas from both 23S rRNA and rnpB genes will help researchers to develop better diagnostic tests for hemoplasma infection and study their pathogenicity and effect on cat health. (The Doris Day and Terry Melcher Foundation)

 

Grant ID: EC25F-400

Status: Active

Year Funded: 2025

Amount awarded: $9,200

Investigator: Kritsada Thongmeesee, Sonthaya Tiawsirisup, Chulalongkorn University, Bangkok, Thailand