W10-014: Cat Phenotypic Health and Information Registry (Cat PHIR)

Approximately 32% of households in the United States have a cat. While cats generally succumb to renal disease and cancer in old age, they are also plagued by a variety of infectious diseases. Cats suffer from many behavioral disorders, which are so significant that undesired behavior is one of the leading causes for cats to be placed in animal shelters. The cat lifestyle has become sedentary and indoor, mimicking that of humans. Thus, as found in humans, diabetes, obesity, and asthma are increasing in incidence in cats and are becoming chronic health concerns. As a result, veterinarians are beginning to perform genetic studies in cats. Improved electronic resources, the interest in obtaining genetic information about pets by owners and breeders, and the feasibility of retaining sufficient DNA sources all support the establishment of a focused system that can be used by researchers to develop disease projects in the cat. Here we propose to coordinate the health information, DNA banking, and cat pedigrees into an electronic, online database system that will assist the collection of individual data for complex disease studies. The resource development proposed will augment research for feline diseases, support clinical and laboratory-based research, and teaching within the veterinary community, and support the development of grant applications to funding agencies. This proposal will continue to develop resources that can be used not only by veterinary researchers, but will also be at the cutting edge of genomic technologies for more complex studies in the cat. The proposed name for the database system is the Cat Phenotypic and Health Information Registry (Cat PHIR).

Grant ID: W10-014

Status: Active

Year Funded: 2010

Amount awarded: $14,000

Investigator: Leslie A. Lyons, PhD; University of California-Davis