Understanding Feline Calicivirus

Winn Funded Research

Ossiboff, R. J. and J. S. Parker (2007). “Identification of regions and residues in feline junctional adhesion molecule required for feline calicivirus binding and infection.” J Virol 81(24): 13608-21.

Despite including important human and animal pathogens, the Caliciviridae family is relatively understudied. Feline caliciviruses (FCVs), members of the Vesivirus genus, are highly contagious pathogens that cause a variety of mild to severe disease syndromes in cats. Virus entry often requires multiple interactions between virus particles and cell surface receptors. These interactions are critical determinants of productive virus entry and are often important factors in viral pathogenesis.

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