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Tissue Doppler Imaging for Feline HCM

Koffas, H., J. Dukes-McEwan, et al. (2008). “Colour M-mode tissue Doppler imaging in healthy cats and cats with hypertrophic cardiomyopathy.” J Small Anim Pract 49(7): 330-338.

Hypertrophic cardiomyopathy (HCM) is the most common heart disease of cats. It appears to be hereditary in some families of cats, and genetic mutations causing HCM have been identified in the Maine Coon cat and Ragdoll cat. Definitive diagnosis of HCM is accomplished by ultrasound imaging. Tissue Doppler imaging (TDI) is a tool for quantification of myocardial function, and has been used in humans, dogs and cats. TDI may allow for improved identification of myocardial functional abnormalities, and may be superior to conventional ultrasound for identification of cats affected with HCM. Colour M-mode TDI is one of the applications of the TDI technique that has not yet been studied in cats. This prospective study was carried out to investigate the differences in some of the colour M-mode TDI indices between normal cats and cats with HCM. We hypothesised that these new TDI techniques would discriminate between the healthy and the diseased myocardium. Myocardial velocity gradient and mean myocardial velocities were measured by colour M-mode TDI in the left ventricular free wall of 20 normal cats and 17 cats with HCM. The study showed that myocardial velocity gradients recorded by colour M-mode TDI can discriminate between the healthy and diseased myocardium. This technique shows promise for discriminating normal from affected cats when screening cats for HCM.
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Related articles:
Simpson, K. E., B. C. Devine, et al. (2007). “Assessment of the repeatability of feline echocardiography using conventional echocardiography and spectral pulse-wave Doppler tissue imaging techniques.” Vet Radiol Ultrasound 48(1): 58-68.
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Koffas, H., J. Dukes-McEwan, et al. (2003). “Peak mean myocardial velocities and velocity gradients measured by color m-mode tissue doppler imaging in healthy cats.” J Vet Intern Med 17(4): 510-524.
>> PubMed Abstract