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Thymoma in a Cat

Fidel, J. L., I. S. Pargass, et al. (2008). “Granulocytopenia associated with thymoma in a domestic shorthaired cat.” J Am Anim Hosp Assoc 44(4): 210-7.

Thymomas are uncommon tumours generally found in senior cats (median age 9.5 years). Diseases reportedly associated with thymomas in cats include paraneoplastic disorders, autoimmune diseases, myasthenia gravis, and exfoliative dermatitis. Granulocytopenia is reported to occur in humans with thymoma but has never been reported in cats. In this case report, a 5-year old spayed female cat with a mass in the cranial mediastinum was diagnosed with thymoma on biopsy of the mass. The tumor was treated with radiation therapy and responded well, but immune-mediated granulocytopenia developed. The granulocytopenia was successfully treated with prednisone and cyclosporine, eventually allowing for surgical removal of the thymoma.
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Related articles:
Zitz, J. C., S. J. Birchard, et al. (2008). “Results of excision of thymoma in cats and dogs: 20 cases (1984-2005).” J Am Vet Med Assoc 232(8): 1186-92.
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