Ramipril treatment for feline HCM

Winn Funded Research

MacDonald, K. A., M. D. Kittleson, et al. (2006). “The effect of ramipril on left ventricular mass, myocardial fibrosis, diastolic function, and plasma neurohormones in Maine Coon cats with familial hypertrophic cardiomyopathy without heart failure.” J Vet Intern Med 20(5): 1093-105.

Hypertrophic cardiomyopathy (HCM) is the most common heart disease of cats, resulting in left ventricular (LV) hypertrophy, myocardial fibrosis, and diastolic dysfunction. [The hypothesis:] Ramipril will reduce LV mass, improve diastolic function, and reduce myocardial fibrosis in cats with HCM without congestive heart failure (CHF).
>> PubMed abstract