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Feline Vaccine-Associated Sarcoma Treatment

Eckstein, C., F. Guscetti, et al. (2009). “A retrospective analysis of radiation therapy for the treatment of feline vaccine-associated sarcoma.” Vet Comp Oncol 7(1): 54-68.

Feline vaccine-associated sarcomas occur in about 1 in 10,000 vaccinated cats, comprise about 40% of all skin tumors, and are the most frequent skin tumor in cats. These tumors are highly invasive and rapidly growing. This study, among other goals, examined the effect of curative radiation treatment on survival time after surgery. Curative treatment (higher dosages, more frequent administration) did improve outcome. Cats with a poorer prognosis and given reduced radiation therapy benefited from the addition of chemotherapy by increased survival time. Both protocols are legitimate options for vaccine-associated sarcomas. [MK]
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Related articles:
Kass, P. H., W. L. Spangler, et al. (2003). “Multicenter case-control study of risk factors associated with development of vaccine-associated sarcomas in cats.” J Am Vet Med Assoc 223(9): 1283-92.
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Romanelli, G., L. Marconato, et al. (2008). “Analysis of prognostic factors associated with injection-site sarcomas in cats: 57 cases (2001-2007).” J Am Vet Med Assoc 232(8): 1193-9.
>> PubMed Abstract