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Feline Injection-Site Sarcomas

Phelps HA, Kuntz CA, Milner RJ et al: Radical excision with five-centimeter margins for treatment of feline injection-site sarcomas: 91 cases (1998–2002), J Am Vet Med Assoc 239:97, 2011.

This study is a retrospective case series of 91 cats with injection-site sarcomas (ISS). The authors evaluated the outcomes of radical excision of the ISS by local recurrence and metastasis rates, survival times, and complications associated with surgery. Rates reported in the literature for local recurrence of feline ISS after treatment range from 26% to 59%. There are no current studies evaluating the outcome of consistently performed radical excision without adjuvant treatment for feline ISS. For this study, radical excision was defined as tumor resection including 5-cm margins surrounding the palpable tumor edge and two fascial planes or bone deep to the tumor. The overall median survival time was 901 days. Fourteen percent of the cats had local tumor recurrence; 18% had evidence of metastasis after surgery. Metastasis significantly affected overall survival with pulmonary metastasis as the most common form. The study reported a major complication rate of 11%, with wound dehiscence being the most commonly encountered problem; none of the complications were fatal. The recurrence rate for this study appeared to be substantially less than rates reported with less aggressive surgeries, suggesting that radical excision may be valuable as a means to achieving an improved outcome in the treatment of ISS in cats. [VT]

Related articles:
Shaw SC, Kent MS, Gordon IK et al: Temporal changes in characteristics of injection-site sarcomas in cats: 392 cases (1990-2006), J Am Vet Med Assoc 234:376, 2009.