Chung TH, Ryu MH, Kim DY et al: Topical tacrolimus (FK506) for the treatment of feline idiopathic facial dermatitis, Aust Vet J 87:417, 2009.
A severe form of pruritic facial dermatitis has been identified in Persian cats. Affected cats have dermatitis around the eyes, nose, and chin with a black waxy discharge. It has proven very difficult to manage in most cats, and the underlying cause is unknown. Tacrolimus is an immunosuppressive drug derived from a soil bacterium. In people, it has been used for treatment of dermatitis, especially eczema and vitiligo. Use of the drug in cats has not been well studied. This case report describes a 3-year-old neutered male Persian cat with chronic ulcerative facial dermatitis diagnosed in Seoul, South Korea. Initial treatment with antimicrobial drugs for secondary infections produced some improvement. The cat was then treated with 0.1% topical tacrolimus ointment. The authors state the patient has been managed effectively with this drug without adverse effects. [SL]
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Fontaine J, Heimann M: Idiopathic facial dermatitis of the Persian cat: three cases controlled with cyclosporine, Veterinary Dermatology 15:64, 2004.