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Feline Gingivostomatitis

Dowers KL, Hawley JR, Brewer MM et al: Association of Bartonella species, feline calicivirus, and feline herpesvirus 1 infection with gingivostomatitis in cats, Journal of Feline Medicine & Surgery 12:314, 2010.

Feline gingivostomatitis (FGS) is a common and devastating disease in cats that results in painful erosive lesions in the throat, oral mucosa, tongue, and gingiva. In many situations, there is not a cure and therapy must be intermittent or chronic. Three of the more common differential diagnoses are feline calicivirus (FCV), feline herpesvirus 1 (FHV-1), and Bartonella species. A total of 131 client-owned cats were involved in this study, 70 of which had FGS confirmed by histopathology and 61 healthy control cats. Results of this study did not find an association between Bartonella species test results (Bartonella species antibodies and DNA in the blood and tissues) and the presence of FGS. Additionally, detection of FHV-1 DNA was not significantly different between groups. With FCV, RNA was present in significantly more cats with FGS (40.5%) than the control cats (0%). This would suggest that in some of the cats, FCV was associated with FGS. An association could not be shown however between FCV RNA in tissues and lesion severity or location. [VT]

Related articles:
Quimby JM, Elston T, Hawley J et al: Evaluation of the association of Bartonella species, feline herpesvirus 1, feline calicivirus, feline leukemia virus and feline immunodeficiency virus with chronic feline gingivostomatitis, J Feline Med Surg 10:66, 2008.