Giori L, Giordano A, Giudice C et al: Performances of different diagnostic tests for feline infectious peritonitis in challenging clinical cases, J Small Anim Pract 52:152, 2011.
Feline infectious peritonitis (FIP) can be difficult to diagnose, especially in cases without abdominal fluid accumulation (‘dry’ or non-effusive FIP). The gold standard for diagnosis is through tissue analysis of involved organs, which is difficult and potentially dangerous in an ill cat. These researchers evaluated the usefulness of several non-invasive assays for diagnosis of FIP. Twelve cases suspicious for FIP, of which eight were confirmed, were evaluated retrospectively. The levels of certain inflammatory proteins were elevated significantly and consistently in cats with FIP. While not confirmatory, measurement of alpha-1-acid glycoprotein (AGP) can be used to support a diagnosis of FIP. [MK]