Six R, Cleaver DM, Lindeman CJ, et al. Effectiveness and safety of cefovecin sodium, an extended-spectrum injectable cephalosporin, in the treatment of cats with abscesses and infected wounds. J Am Vet Med Assoc. Jan 1 2009;234(1):81-87.
Abscesses and infected bite or scratch wounds are very common problems in feline medicine. The most common pathogen involved is Pasteurella multocida. Treatment of infected wounds is accomplished by drainage and debridement, and antibiotic therapy. Antibiotics typically recommended for first line treatment include penicillins, cephalosporins, and clindamycin. These drugs require once or twice daily dosing, and treatment must be continued for 7 to 14 days. Cefovecin (Convenia, Pfizer Animal Health) is a new extended-spectrum bactericidal cephalosporin. The manufacturer recommends a one-time subcutaneous injection at a dose of 8 mg/kg. Therapeutic concentrations of the drug against P. multocida are maintained for approximately 7 days. This multicenter, randomized, double-blinded, controlled clinical trial was designed to evaluate the effectiveness and safety of cefovecin in the treatment of cats with abscesses and infected wounds. Cats were randomly allocated to one of two groups. One group received a single dose of cefovecin followed by placebo drops orally once daily for 14 days. The second group received one subcutaneous placebo injection followed by cefadroxil once daily for 14 days. The effectiveness of cefovecin was similar to that of cefadroxil. At day 28, 97% of cefovecin-treated cats and 91% of cefadroxil-treated cats were considered treatment successes. There were no serious adverse effects reports. >> PubMed Abstract
Related articles: Stegemann MR, Sherington J, Passmore C. The efficacy and safety of cefovecin in the treatment of feline abscesses and infected wounds. J Small Anim Pract. Dec 2007;48(12):683-689. >>PubMed Abstract
Stegemann MR, Sherington J, Coati N, Brown SA, Blanchflower S. Pharmacokinetics of cefovecin in cats. J Vet Pharmacol Ther. Dec 2006;29(6):513-524. >>PubMed Abstract
To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
Functional Always active
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
Preferences
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
Statistics
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
Marketing
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.
To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
Functional Always active
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
Preferences
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
Statistics
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
Marketing
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.
