Meurs, K. M., M. M. Norgard, et al. (2007). “A substitution mutation in the myosin binding protein C gene in ragdoll hypertrophic cardiomyopathy.” Genomics 90(2): 261-4.
Familial hypertrophic cardiomyopathy (HCM) is a primary myocardial disease with a prevalence of 1 in 500 in human beings. Heritable HCM also exists in a large-animal model, the cat, and we have previously reported a mutation in the MYBPC3 gene in the Maine coon breed. We now report a separate mutation in the MYBPC3 gene in ragdoll cats with HCM.
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